Product Description
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.
Information
ApplicationWB, IHC, IF, IP, FC
Research AreaCancer, MAPK pathway, Neuroscience, Immunology, Innate Immunity, Neurodegeneration, MAPK/p38 pathway, MAPK/ERK pathway, Epigenetics,
Species ReactivityHuman, Mouse, Rat, Monkey
Host SpeciesRabbit
IsotypeIgG
Specifications
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended DilutionWB 1:1000 - 1:4000
IHC 1:50 - 1:200
IF 1:50 - 1:100
IP 1:20 - 1:50
FC 1:20 - 1:50
Misc Information
Storage InstructionStore at -20℃. Avoid freeze / thaw cycles.
Alternative NamesCREB;CREB-1
Calculated Molecular Weight25kDa/35kDa/36kDa
PurificationAffinity purification
Cellular LocationNucleus,