tcsc6451 GSK3326595

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Product Description

GSK3326595 is a potent, selective, reversible inhibitor of protein arginine methyltransferase 5 (PRMT5) with an IC50 of 6.2 nM.

IC50 & Target: IC50: 6.2 nM (PRMT5)[1]

In Vitro: GSK3326595 (EPZ015938), has entered clinical trials for the treatment of solid tumors and non-Hodgkin’s lymphoma[1].

Information

CAS No1616392-22-3
FormulaC24H32N6O3
Clinical Informationclinicalinformation
PathwayEpigenetics
TargetHistone Methyltransferase

Specifications

Purity / Grade>98%
SolubilityDMSO : ≥ 30 mg/mL (66.29 mM)
Smilessmiles

Misc Information

Alternative NamesEPZ015938
Observed Molecular Weight452.55
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