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BioChemicals
Mertansine
tcsc5804
Mertansine
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AVAILABLE SIZES
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$
94.00
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ORDERING INFORMATION
International
TAICLONE BIOTECH CORP.
order@taiclone.com
+886-2-2735-9682
+886-2-2735-9807
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Product Description
Mertansine (DM1) is a
microtubulin
inhibitor which binds at the tips of microtubules and suppresses the dynamicity of microtubules.. Mertansine is an antibody-conjugatable maytansinoid that was developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.
Information
CAS No
139504-50-0
Formula
C
35
H
48
ClN
3
O
10
S
Clinical Information
clinicalinformation
Pathway
Cell Cycle/DNA Damage
Cytoskeleton
Antibody-drug Conjugate/ADC Related
Target
Microtubule/Tubulin
Microtubule/Tubulin
Drug-Linker Conjugates for ADC
Specifications
Purity / Grade
>98%
Solubility
H2O : < 0.1 mg/mL (insoluble); DMSO : ≥ 83.33 mg/mL (112.87 mM)
Smiles
smiles
Misc Information
Alternative Names
DM1;Maytansinoid DM1
Observed Molecular Weight
738.29
related data
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