tcsc5637 Tirabrutinib (hydrochloride)

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Product Description

Tirabrutinib (ONO-4059) hydrochloride is a selective and novel inhibitor of BTK with IC50 2.2 nm, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development.

IC50 & Target: IC50: 2.2 nM (BTK)[1].

Information

CAS No1439901-97-9
FormulaC25H23ClN6O3
Clinical Informationclinicalinformation
PathwayProtein Tyrosine Kinase/RTK
TargetBtk

Specifications

Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles

Misc Information

Alternative NamesONO-4059 (hydrochloride);GS-4059 (hydrochloride)
Observed Molecular Weight490.94
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