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BioChemicals
Pexidartinib (PLX-3397)
tcsc4256
Pexidartinib
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AVAILABLE SIZES
5mg
10mg
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200mg
$
71.00
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ORDERING INFORMATION
International
TAICLONE BIOTECH CORP.
order@taiclone.com
+886-2-2735-9682
+886-2-2735-9807
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Product Description
Pexidartinib is a receptor tyrosine kinase (RTK) inhibitor of
KIT
, CSF1R and FLT3, with potential antineoplastic activity, with
IC
50
of 28 and 16 nM for Fms and Kit, respectively.
IC50 & Target: IC50: 28 nM (c-Fms), 16 nM (c-Kit)
In Vivo:
Pexidartinib is a potent drug for treatment of cancer and used for Phase III TGCT clinical trial
[1]
.
Information
CAS No
1029044-16-3
Formula
C
20
H
15
ClF
3
N
5
Clinical Information
clinicalinformation
Pathway
Protein Tyrosine Kinase/RTK
Protein Tyrosine Kinase/RTK
Target
c-Fms
c-Kit
Specifications
Form
White Solid
Purity / Grade
>98.57%
Solubility
DMSO : ≥ 30 mg/mL (71.80 mM)
Smiles
smiles
Misc Information
Storage Instruction
Powder -20℃ for 3 years
In solvent -80℃ for 12 months
Alternative Names
PLX-3397
Observed Molecular Weight
417.81
related data
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