tcsc3292 WH-4-023

WH-4-023 is a potent and selective dual Lck/Src inhibitor with IC₅₀ of 2 nM/6 nM for Lck and Src kinase respectively; little inhibition on p38α and KDR.











IC50 & Target: IC50: 2 nM (Lck), 6 nM (Src)^[1]

In Vitro: WH-4-023 shows a similar potency increase on Lck as 2-substituted variants^[1].