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Product Description
Lomefloxacin HCl is a fluoroquinolone antibiotic.
Target: Antibacterial
Lomefloxacin is a bactericidal fluoroquinolone agent with activity against a wide range of gram-negative and gram-positive organisms. The bactericidal action of lomefloxacin results from interference with the activity of the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase appears to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV appears to be the preferential target in gram-positive organisms. Interference with these two topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. As a result DNA replication and transcription is inhibited [1].
Information
CAS No98079-52-8
FormulaC17H20ClF2N3O3
Clinical Informationclinicalinformation
PathwayAnti-infection
TargetBacterial
Specifications
Purity / Grade>98%
SolubilityH2O : 10 mg/mL (25.79 mM; Need ultrasonic and warming)
Smilessmiles
Misc Information
Observed Molecular Weight387.81
related data
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