tcsc2216 Meclofenoxate (hydrochloride)

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Product Description

Meclofenoxate hydrochloride, an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA), has been shown to improve memory, have a mentally stimulating effect, and improve general cognition.

IC50 value:

Target: nootropic

Meclofenoxate, administered in a dose of 50 mg/kg twice daily for 7 days using the maze-training method, increased the number of responses to the conditioned stimulus, when retention tests were made 24 hours and 7 days after training, whereas citicholine, applied in the same way in a dose of 10 mg/kg, shortened the latency of the responses with reinforcement during the training and increased the number of correct responses to the conditioned stimulus in retention tests 7 days after the training [1]. Meclofenoxate appears to increase the consolidation of new information into long-term memory, but does not affect other aspects of remembering [2].

Information

CAS No3685-84-5
FormulaC12H17Cl2NO3
Clinical Informationclinicalinformation
PathwayNeuronal Signaling
Membrane Transporter/Ion Channel
Membrane Transporter/Ion Channel
Neuronal Signaling
TargetnAChR
nAChR
iGluR
iGluR

Specifications

Purity / Grade>98%
SolubilityH2O : 33.33 mg/mL (113.30 mM; Need ultrasonic); DMSO : ≥ 50 mg/mL (169.97 mM)
Smilessmiles

Misc Information

Observed Molecular Weight294.17
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