tcsc1334 Poloxime

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Data sheet

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Product Description

Poloxime, a hydrolysis product of poloxin, is a non-ATP-competitive Plk1 inhibitor, with moderate Plk1 inhibitory activity.

IC50 & Target: PLK1[1]

In Vitro: Poloxime (100 μM) inhibits phosphopeptide binding to polo-box domain (PBD) of polo-like kinase 1 (Plk1)[2].

Information

CAS No17302-61-3
FormulaC10H13NO2
Clinical Informationclinicalinformation
PathwayCell Cycle/DNA Damage
TargetPolo-like Kinase (PLK)

Specifications

Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles

Misc Information

Observed Molecular Weight179.22
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