In Vitro: The newly synthesized bisbenzimidazole derivatives DMA (6c) is evaluated for their cytotoxicity against human tumor cell lines, which are cervix carcinoma cell line (HeLa), breast carcinoma cell line (MCF7) and brain glioma cell line (U87) in comparison to Hoechst. In case of MCF7, the IC50 is observed at 5.3 μM for DMA. The IC50 determined in the case of HeLa is 3.4 μM for DMA[1].
Information
CAS No188860-26-6
FormulaC27H28N6O2
Clinical Informationclinicalinformation
PathwayOthers
TargetOthers
Specifications
Purity / Grade>98%
SolubilityDMSO : ≥ 54 mg/mL (115.25 mM)
Smilessmiles
Misc Information
Observed Molecular Weight468.55
related data
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