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Product Description
A-317491 is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux mediated by the receptors.
IC50 value:
Target: P2X2/3 receptor
It is known that P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Studies indicate that the P2X3 receptor is implicated in both neuropathic and inflammatory pain. P2X3 receptor is a promising target for therapeutic intervention in cancer patients for pain management.
Information
FormulaC33H29NNaO9
Clinical Informationclinicalinformation
PathwayMembrane Transporter/Ion Channel Autophagy
TargetP2X Receptor Autophagy
Specifications
Purity / Grade>98%
SolubilityH2O : ≥ 100 mg/mL (164.86 mM)
Smilessmiles
Misc Information
Observed Molecular Weight606.57
related data
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