tcsc1227 Voriconazole

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Product Description

Voriconazole(UK-109496) is a second-generation triazole antifungal used to treat serious fungal infections.

IC50 Value:

Target: Antifungal

Voriconazole displays potent activity against Candida, Cryptococcus and Aspergillus species. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.

Information

CAS No137234-62-9
FormulaC16H14F3N5O
Clinical Informationclinicalinformation
PathwayAnti-infection
TargetFungal

Specifications

Purity / Grade>98%
SolubilityDMSO : ≥ 50 mg/mL (143.14 mM); H2O : 0.17 mg/mL (0.49 mM; Need ultrasonic)
Smilessmiles

Misc Information

Alternative NamesUK-109496
Observed Molecular Weight349.31
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