tcsc1103 Etifoxine (hydrochloride)

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Product Description

Etifoxine Hcl(HOE 36-801) is potentiator of GABAA receptor function in cultured neurons. Etifoxine preferentially acts on β2 or β3 subunit-containing GABAA receptors.

IC50 value:

Target: GABAA receptor

Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Etifoxine acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration.

Information

CAS No56776-32-0
FormulaC17H18Cl2N2O
Clinical Informationclinicalinformation
PathwayNeuronal Signaling
Membrane Transporter/Ion Channel
TargetGABA Receptor
GABA Receptor

Specifications

Purity / Grade>98%
SolubilityDMSO : 50 mg/mL (148.26 mM; Need ultrasonic)
Smilessmiles

Misc Information

Alternative NamesHOE 36-801
Observed Molecular Weight337.24
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