tcsc0857 Setiptiline (maleate)

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Data sheet

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Product Description

Setiptiline is a serotonin receptor antagonist.

IC50 value:

Target: 5-HT receptor

Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine. From Wikipedia.

Information

CAS No85650-57-3
FormulaC23H23NO4
Clinical Informationclinicalinformation
PathwayNeuronal Signaling
GPCR/G Protein
Target5-HT Receptor
5-HT Receptor

Specifications

Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles

Misc Information

Alternative NamesMO-8282
Observed Molecular Weight377.43
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