tcsc0847 Calcifediol (monohydrate)

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Product Description

Calcifediol (monohydrate) is a major circulating metabolite of vitamin D3, acting as a competitive inhibitor with an apparent Ki of 3.9 μM, suppresses PTH secretion and mRNA (ED50=2 nM).

In Vitro: Calcifediol in either liposomes or ethanolic solution has no effect on the release of the proinflammatory cytokine KC from Pseudomonas-infected murine epithelial cells. Treatment of infected, human bronchial 16-HBE cells with Calcifediol liposomes results in a significant reduction in bacterial survival[1]

Information

CAS No63283-36-3
FormulaC27H46O3
Clinical Informationclinicalinformation
PathwayVitamin D Related
TargetVD/VDR

Specifications

Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles

Misc Information

Alternative Names25-hydroxy Vitamin D3 monohydrate
Observed Molecular Weight418.65
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