tcsc0690 Dipraglurant

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Product Description

Dipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM.

IC50 Value: 0.021 μM [1]

Target: mGluR

Dipraglurant (ADX-48621) from Addex Therapeutics showed in vivo activity in different anxiety models in rat50 and is currently in phase II for the treatment of dyskinesia in Parkinson's disease.

Information

CAS No872363-17-2
FormulaC16H12FN3
Clinical Informationclinicalinformation
PathwayGPCR/G Protein
TargetmGluR

Specifications

Purity / Grade>98%
SolubilityDMSO : ≥ 40 mg/mL (150.78 mM)
Smilessmiles

Misc Information

Alternative NamesADX48621
Observed Molecular Weight265.29
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