tcsc0484 ARRY-380 (analog )

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Product Description

The product is the analog of ARRY-380, ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR

Information

CAS No937265-83-3
FormulaC29H27N7O4S
Clinical Informationclinicalinformation
PathwayJAK/STAT Signaling
Protein Tyrosine Kinase/RTK
TargetEGFR
EGFR

Specifications

Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles

Misc Information

Observed Molecular Weight569.63
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