tcsc0342 Pim1 / AKK1-IN-1

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Product Description

Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.

IC50 & Target: Kd: 35 nM (Pim1), 53 nM (AKK1), 75 nM (MST2), 380 nM (LKB1)

In Vitro: Pim1/AKK1-IN-1 is multi-kinase inhibitor, and has Kd of 380 nM against LKB1 and 53 nM against AAK1[1].

Information

CAS No1093222-27-5
FormulaC20H13N5O
Clinical Informationclinicalinformation
PathwayJAK/STAT Signaling
TargetPim

Specifications

Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles

Misc Information

Alternative NamesLKB1/AAK1 dual inhibitor
Observed Molecular Weight339.35
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