tcsc0039434 Ketohexokinase inhibitor 1

Ketohexokinase inhibitor 1 is an inhibitor of ketohexokinase (KHK), with IC₅₀s of 8.4 nM and 66 nM for KHK-C and KHK-A, respectively, extracted from patent US 20170183328 A1, example 4.

IC50 & Target: IC50: 8.4 nM (KHK-C), 66 nM (KHK-A)^[1]

In Vitro: Ketohexokinase inhibitor 1 (Example 4) is an inhibitor of ketohexokinase (KHK), with IC₅₀s of 8.4 nM and 66 nM for KHK-C and KHK-A, sepctively^[1].