tcsc0020296 Gramicidin

Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations.

IC50 & Target: Bacterial^[1]

In Vitro: Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. There is poor Gramicidin activity against E. coli and S. cerevisae as shown from the survival of microbes (%) over a range of Gramicidin concentrations, in contrast with the action of Gramicidin on S. aureus. The microbicidal activity occurs over a range of low Gramicidin and DODAB concentrations which are not toxic to S. cerevisae^[1].