tcsc0018136 ICI 211965

ICI 211965 is a selective and orally potent 5-Lipoxygenase (5-LPO) inhibitor.

IC50 & Target: 5-LPO^[1]

In Vitro: ICI 211965 is a selective and orally potent 5-Lipoxygenase (5-LPO) inhibitor. ICI 211965 reduces the leakage of lactate dehydrogenase (LD) and lipid peroxidation at concentrations related to its antioxidative effect and not to its 5-1ipoxygenase-inhibiting effect^[1].