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BioChemicals
Pentiapine
tcsc0018131
Pentiapine
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AVAILABLE SIZES
1mg
5mg
10mg
$
1,073.00
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ORDERING INFORMATION
International
TAICLONE BIOTECH CORP.
order@taiclone.com
+886-2-2735-9682
+886-2-2735-9807
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Product Description
Pentiapine is a novel
dopamine release
inhibitor.
IC50 & Target: Dopamine receptor
[1]
In Vivo:
Pentiapine is a novel dopamine release inhibitor.The results show that Pentiapine dose-dependently reduces motor activity of mice. Moreover, Pentiapine dose-dependently reduces morphine-induced hyperactivity. Newman-Keuls post-hoc comparisons indicate that the group receiving morphine plus saline presents more activity than the groups receiving morphine plus 2 (P<0.05), 4, 8, 16, 24 and 32 (P<0.01) mg/kg of Pentiapine. Moreover, the groups receiving morphine plus 0.5, 1 and 2 mg/kg of Pentiapine present more activity than the groups receiving morphine plus 4, 8, 16, 24 and 32 mg/kg of Pentiapine (P<0.01)
[1]
. 30 mg/kg dose of Pentiapine completely blocks the methylenedioxymethamphetamine (MDMA) conditioned place preference (CPP) and also blocks the establishment of a cocaine CPP
[2]
.
Information
CAS No
81382-51-6
Formula
C
15
H
17
N
5
S
Clinical Information
clinicalinformation
Pathway
GPCR/G Protein
Neuronal Signaling
Target
Dopamine Receptor
Dopamine Receptor
Specifications
Purity / Grade
>98%
Solubility
10 mM in DMSO
Smiles
smiles
Misc Information
Alternative Names
CGS 10746
Observed Molecular Weight
299.39
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