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BioChemicals
Vibunazole
tcsc0018100
Vibunazole
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AVAILABLE SIZES
5mg
10mg
$
214.00
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ORDERING INFORMATION
International
TAICLONE BIOTECH CORP.
order@taiclone.com
+886-2-2735-9682
+886-2-2735-9807
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Product Description
Vibunazole is a new antifungal azole.
In Vitro:
Vibunazole is an antifungal azole. Low concentrations of all three drugs inhibit Coccidioides immitis, strain Silveira,
in vitro
with a descending order of activity ketoconazole>Vibunazole>BAY 1 9139
[1]
.
In Vivo:
The untreated, infected mice lost weight initially and progressively, whereas treated mice gain weight after an initial loss with Vibunazole (all doses), BAY 1 9139 and ketoconazole at 2.5 mg/kg/day. With both Vibunazole and BAY 1 9139, the 5 and 10 mg/kg doses yield serum concentrations exceeding the MICs for the Coccidioides immitis test strain (0.8 and 1.5 μg/mL respectively) for periods in excess of 30 min after injection
[1]
.
Information
CAS No
80456-55-9
Formula
C
15
H
20
ClN
3
O
2
Clinical Information
clinicalinformation
Pathway
Anti-infection
Target
Fungal
Specifications
Purity / Grade
>98%
Solubility
10 mM in DMSO
Smiles
smiles
Misc Information
Alternative Names
BAY-N-7133
Observed Molecular Weight
309.79
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