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Product Description
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Information
ApplicationWB, IHC, IF
Species ReactivityHuman, Mouse, Rat, Monkey
Host SpeciesRabbit
Immunogen / Amino acidsA synthetic peptide of human XRCC6
ConjugationUnconjugated
ClonalityPolyclonal
IsotypeIgG
Specifications
FormLiquid
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
