tcsa17963 Anti RUNX1 Antibody

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Product Description

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Information

ApplicationWB, IHC, IF
Species ReactivityHuman, Mouse, Rat
Host SpeciesRabbit
Immunogen / Amino acidsA synthetic peptide of human RUNX1
ConjugationUnconjugated
ClonalityPolyclonal
IsotypeIgG

Specifications

FormLiquid
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200

Misc Information

Storage InstructionStore at -20C. Avoid freeze / thaw cycles.
Alternative NamesRUNX1 antibody
Runt-related transcription factor 1 antibody
Acute myeloid leukemia 1 protein antibody
Core-binding factor subunit alpha-2 antibody
CBF-alpha-2 antibody
Oncogene AML-1 antibody
Polyomavirus enhancer-binding protein 2
SwissProtQ01196
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