tcsa17587 Anti OLR1 Antibody

Western blot analysis of extracts of various cell lines, using OLR1 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.Immunohistochemistry of paraffin-embedded human gastric cancer using OLR1 Antibody at dilution of 1:200 (40x lens).Immunohistochemistry of paraffin-embedded human stomach using OLR1 Antibody at dilution of 1:200 (40x lens).Immunohistochemistry of paraffin-embedded mouse testis using OLR1 Antibody at dilution of 1:200 (40x lens).Immunohistochemistry of paraffin-embedded human kidney using OLR1 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded rat brain using OLR1 Antibody at dilution of 1:200 (40x lens).Immunohistochemistry of paraffin-embedded rat spleen using OLR1 Antibody at dilution of 1:200 (40x lens).Immunohistochemistry of paraffin-embedded human kidney using OLR1 Antibody at dilution of 1:200 (40x lens).Immunohistochemistry of paraffin-embedded human stomach using OLR1 Antibody at dilution of 1:200 (40x lens).Immunohistochemistry of paraffin-embedded human gastric cancer using OLR1 Antibody at dilution of 1:200 (40x lens).Immunohistochemistry of paraffin-embedded mouse intestine using OLR1 Antibody at dilution of 1:200 (40x lens).Immunohistochemistry of paraffin-embedded mouse testis using OLR1 Antibody at dilution of 1:200 (40x lens).
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Product Description

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

Information

ApplicationWB, IHC
Species ReactivityHuman, Mouse, Rat
Host SpeciesRabbit
Immunogen / Amino acidsRecombinant protein of human OLR1
ConjugationUnconjugated
ClonalityPolyclonal
IsotypeIgG

Specifications

FormLiquid
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200

Misc Information

Storage InstructionStore at -20C. Avoid freeze / thaw cycles.
Alternative NamesOLR1 antibody
Oxidized low-density lipoprotein receptor 1 antibody
Ox-LDL receptor 1 antibody
C-type lectin domain family 8 member A antibody
Lectin-like oxidized LDL receptor 1 antibody
LOX-1 antibody
Lectin-like oxLDL receptor 1
SwissProtP78380
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