tcsa17519 Anti NFKB2 Antibody

Western blot analysis of extracts of various cell lines, using NFKB2 antibody at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.Immunohistochemistry of paraffin-embedded rat liver using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded rat testis using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded human liver cancer using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded human liver injury using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded human vermiform appendix using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded human breast cancer using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded human kidney cancer using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded human gastric cancer using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded mouse lung using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded mouse liver using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded mouse brain using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded mouse kidney using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded human uterine cancer using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded rat lung using NFKB2 Antibody at dilution of 1:100 (40x lens).Immunohistochemistry of paraffin-embedded rat liver using NFKB2 Antibody at dilution of 1:100 (40x lens).
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Product Description

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

Information

ApplicationWB, IHC
Species ReactivityHuman, Mouse, Rat
Host SpeciesRabbit
Immunogen / Amino acidsA synthetic peptide of human NFKB2
ConjugationUnconjugated
ClonalityPolyclonal
IsotypeIgG

Specifications

FormLiquid
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200

Misc Information

Storage InstructionStore at -20C. Avoid freeze / thaw cycles.
Alternative NamesNFKB2 antibody
Nuclear factor NF-kappa-B p100 subunit antibody
DNA-binding factor KBF2 antibody
H2TF1 antibody
Lymphocyte translocation chromosome 10 protein antibody
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
SwissProtQ00653
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